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Other Conditions With Symptoms Similar to Lupus

Several conditions may be confused with lupus (systemic lupus erythematosus, or SLE). They share some but not all of the symptoms of lupus. For example, rheumatoid arthritis begins with joint pain and swelling, and fibromyalgia begins with fatigue and joint pain. But as the condition continues, people with lupus develop skin rashes or symptoms in other organs, such as the heart, lungs, or kidneys, and will test positive for antibodies produced by the immune system that help to identify lupus.

Conditions that may have symptoms similar to lupus include:

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Arthritis (joint pain and restriction of movement), such as rheumatoid arthritis.
Fibromyalgia, a disease of the muscles and joints that causes pain and stiffness.
Glomerulonephritis, inflammation of the kidneys.
Scleroderma, a disease of the body's connective tissue.
Sjögren's syndrome, a condition that causes dry mouth and dry eyes, and is often associated with rheumatoid arthritis.
Chronic fatigue syndrome, a condition of severe, long-term fatigue.
Vasculitis, inflammation of the blood vessels.

By	Healthwise Staff
Primary Medical Reviewer	Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer	Stanford M. Shoor, MD - Rheumatology
Last Revised	May 7, 2010

WebMD Medical Reference from Healthwise

Last Updated: May 07, 2010

This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.